The recent success of general-domain large language models (LLMs) has significantly changed the natural language processing paradigm towards a unified foundation model across domains and applications. In this paper, we focus on assessing the performance of GPT-4, the most capable LLM so far, on the text-based applications for radiology reports, comparing against state-of-the-art (SOTA) radiology-specific models. Exploring various prompting strategies, we evaluated GPT-4 on a diverse range of common radiology tasks and we found GPT-4 either outperforms or is on par with current SOTA radiology models. With zero-shot prompting, GPT-4 already obtains substantial gains (≈ 10% absolute improvement) over radiology models in temporal sentence similarity classification (accuracy) and natural language inference (F₁). For tasks that require learning dataset-specific style or schema (e.g. findings summarisation), GPT-4 improves with example-based prompting and matches supervised SOTA. Our extensive error analysis with a board-certified radiologist shows GPT-4 has a sufficient level of radiology knowledge with only occasional errors in complex context that require nuanced domain knowledge. For findings summarisation, GPT-4 outputs are found to be overall comparable with existing manually-written impressions.

As the Internet grows in size, so does the amount of text based information that exists. For many application spaces it is paramount to isolate and identify texts that relate to a particular topic. While one-class classification would be ideal for such analysis, there is a relative lack of research regarding efficient approaches with high predictive power. By noting that the range of documents we wish to identify can be represented as positive linear combinations of the Vector Space Model representing our text, we propose Conical classification, an approach that allows us to identify if a document is of a particular topic in a computationally efficient manner. We also propose Normal Exclusion, a modified version of Bi-Normal Separation that makes it more suitable within the one-class classification context. We show in our analysis that our approach not only has higher predictive power on our datasets, but is also faster to compute.