Jean-Benoit Delbrouck

Also published as: Jean-benoit Delbrouck


2024

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RadGraph-XL: A Large-Scale Expert-Annotated Dataset for Entity and Relation Extraction from Radiology Reports
Jean-Benoit Delbrouck | Pierre Chambon | Zhihong Chen | Maya Varma | Andrew Johnston | Louis Blankemeier | Dave Van Veen | Tan Bui | Steven Truong | Curtis Langlotz
Findings of the Association for Computational Linguistics: ACL 2024

In order to enable extraction of structured clinical data from unstructured radiology reports, we introduce RadGraph-XL, a large-scale, expert-annotated dataset for clinical entity and relation extraction. RadGraph-XL consists of 2,300 radiology reports, which are annotated with over 410,000 entities and relations by board-certified radiologists. Whereas previous approaches focus solely on chest X-rays, RadGraph-XL includes data from four anatomy-modality pairs - chest CT, abdomen/pelvis CT, brain MR, and chest X-rays. Then, in order to automate structured information extraction, we use RadGraph-XL to train transformer-based models for clinical entity and relation extraction. Our evaluations include comprehensive ablation studies as well as an expert reader study that evaluates trained models on out-of-domain data. Results demonstrate that our model surpasses the performance of previous methods by up to 52% and notably outperforms GPT-4 in this domain. We release RadGraph-XL as well as our trained model to foster further innovation and research in structured clinical information extraction.

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GREEN: Generative Radiology Report Evaluation and Error Notation
Sophie Ostmeier | Justin Xu | Zhihong Chen | Maya Varma | Louis Blankemeier | Christian Bluethgen | Arne Edward Michalson Md | Michael Moseley | Curtis Langlotz | Akshay S Chaudhari | Jean-Benoit Delbrouck
Findings of the Association for Computational Linguistics: EMNLP 2024

Evaluating radiology reports is a challenging problem as factual correctness is extremely important due to its medical nature. Existing automatic evaluation metrics either suffer from failing to consider factual correctness (e.g., BLEU and ROUGE) or are limited in their interpretability (e.g., F1CheXpert and F1RadGraph). In this paper, we introduce GREEN (Generative Radiology Report Evaluation and Error Notation), a radiology report generation metric that leverages the natural language understanding of language models to identify and explain clinically significant errors in candidate reports, both quantitatively and qualitatively. Compared to current metrics, GREEN offers: 1) a score aligned with expert preferences, 2) human interpretable explanations of clinically significant errors, enabling feedback loops with end-users, and 3) a lightweight open-source method that reaches the performance of commercial counterparts. We validate our GREEN metric by comparing it to GPT-4, as well as to error counts of 6 experts and preferences of 2 experts. Our method demonstrates not only higher correlation with expert error counts, but simultaneously higher alignment with expert preferences when compared to previous approaches.

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Overview of the First Shared Task on Clinical Text Generation: RRG24 and “Discharge Me!”
Justin Xu | Zhihong Chen | Andrew Johnston | Louis Blankemeier | Maya Varma | Jason Hom | William J. Collins | Ankit Modi | Robert Lloyd | Benjamin Hopkins | Curtis Langlotz | Jean-Benoit Delbrouck
Proceedings of the 23rd Workshop on Biomedical Natural Language Processing

Recent developments in natural language generation have tremendous implications for healthcare. For instance, state-of-the-art systems could automate the generation of sections in clinical reports to alleviate physician workload and streamline hospital documentation. To explore these applications, we present a shared task consisting of two subtasks: (1) Radiology Report Generation (RRG24) and (2) Discharge Summary Generation (“Discharge Me!”). RRG24 involves generating the ‘Findings’ and ‘Impression’ sections of radiology reports given chest X-rays. “Discharge Me!” involves generating the ‘Brief Hospital Course’ and '‘Discharge Instructions’ sections of discharge summaries for patients admitted through the emergency department. “Discharge Me!” submissions were subsequently reviewed by a team of clinicians. Both tasks emphasize the goal of reducing clinician burnout and repetitive workloads by generating documentation. We received 201 submissions from across 8 teams for RRG24, and 211 submissions from across 16 teams for “Discharge Me!”.

2023

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Toward Expanding the Scope of Radiology Report Summarization to Multiple Anatomies and Modalities
Zhihong Chen | Maya Varma | Xiang Wan | Curtis Langlotz | Jean-Benoit Delbrouck
Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 2: Short Papers)

Radiology report summarization (RRS) is a growing area of research. Given the Findings section of a radiology report, the goal is to generate a summary (called an Impression section) that highlights the key observations and conclusions of the radiology study. However, RRS currently faces essential limitations. First, many prior studies conduct experiments on private datasets, preventing reproduction of results and fair comparisons across different systems and solutions. Second, most prior approaches are evaluated solely on chest X-rays. To address these limitations, we propose a dataset (MIMIC-RRS) involving three new modalities and seven new anatomies based on the MIMIC-III and MIMIC-CXR datasets. We then conduct extensive experiments to evaluate the performance of models both within and across modality-anatomy pairs in MIMIC-RRS. In addition, we evaluate their clinical efficacy via RadGraph, a factual correctness metric.

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RadAdapt: Radiology Report Summarization via Lightweight Domain Adaptation of Large Language Models
Dave Van Veen | Cara Van Uden | Maayane Attias | Anuj Pareek | Christian Bluethgen | Malgorzata Polacin | Wah Chiu | Jean-Benoit Delbrouck | Juan Zambrano Chaves | Curtis Langlotz | Akshay Chaudhari | John Pauly
The 22nd Workshop on Biomedical Natural Language Processing and BioNLP Shared Tasks

We systematically investigate lightweight strategies to adapt large language models (LLMs) for the task of radiology report summarization (RRS). Specifically, we focus on domain adaptation via pretraining (on natural language, biomedical text, or clinical text) and via discrete prompting or parameter-efficient fine-tuning. Our results consistently achieve best performance by maximally adapting to the task via pretraining on clinical text and fine-tuning on RRS examples. Importantly, this method fine-tunes a mere 0.32% of parameters throughout the model, in contrast to end-to-end fine-tuning (100% of parameters). Additionally, we study the effect of in-context examples and out-of-distribution (OOD) training before concluding with a radiologist reader study and qualitative analysis. Our findings highlight the importance of domain adaptation in RRS and provide valuable insights toward developing effective natural language processing solutions for clinical tasks.

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Overview of the RadSum23 Shared Task on Multi-modal and Multi-anatomical Radiology Report Summarization
Jean-Benoit Delbrouck | Maya Varma | Pierre Chambon | Curtis Langlotz
The 22nd Workshop on Biomedical Natural Language Processing and BioNLP Shared Tasks

Radiology report summarization is a growing area of research. Given the Findings and/or Background sections of a radiology report, the goal is to generate a summary (called an Impression section) that highlights the key observations and conclusions of the radiology study. Recent efforts have released systems that achieve promising performance as measured by widely used summarization metrics such as BLEU and ROUGE. However, the research area of radiology report summarization currently faces two important limitations. First, most of the results are reported on private datasets. This limitation prevents the ability to reproduce results and fairly compare different systems and solutions. Secondly, to the best of our knowledge, most research is carried out on chest X-rays. To palliate these two limitations, we propose a radiology report summarization (RadSum) challenge on i) a new dataset of eleven different modalities and anatomies pairs based on the MIMIC-III database ii) a multimodal report summarization dataset based on MIMIC-CXR enhanced with a brand-new test-set from Stanford Hospital. In total, we received 112 submissions across 11 teams.

2022

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ViLMedic: a framework for research at the intersection of vision and language in medical AI
Jean-benoit Delbrouck | Khaled Saab | Maya Varma | Sabri Eyuboglu | Pierre Chambon | Jared Dunnmon | Juan Zambrano | Akshay Chaudhari | Curtis Langlotz
Proceedings of the 60th Annual Meeting of the Association for Computational Linguistics: System Demonstrations

There is a growing need to model interactions between data modalities (e.g., vision, language) — both to improve AI predictions on existing tasks and to enable new applications. In the recent field of multimodal medical AI, integrating multiple modalities has gained widespread popularity as multimodal models have proven to improve performance, robustness, require less training samples and add complementary information. To improve technical reproducibility and transparency for multimodal medical tasks as well as speed up progress across medical AI, we present ViLMedic, a Vision-and-Language medical library. As of 2022, the library contains a dozen reference implementations replicating the state-of-the-art results for problems that range from medical visual question answering and radiology report generation to multimodal representation learning on widely adopted medical datasets. In addition, ViLMedic hosts a model-zoo with more than twenty pretrained models for the above tasks designed to be extensible by researchers but also simple for practitioners. Ultimately, we hope our reproducible pipelines can enable clinical translation and create real impact. The library is available at https://github.com/jbdel/vilmedic.

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Improving the Factual Correctness of Radiology Report Generation with Semantic Rewards
Jean-Benoit Delbrouck | Pierre Chambon | Christian Bluethgen | Emily Tsai | Omar Almusa | Curtis Langlotz
Findings of the Association for Computational Linguistics: EMNLP 2022

Neural image-to-text radiology report generation systems offer the potential to improve radiology reporting by reducing the repetitive process of report drafting and identifying possible medical errors. These systems have achieved promising performance as measured by widely used NLG metrics such as BLEU and CIDEr. However, the current systems face important limitations. First, they present an increased complexity in architecture that offers only marginal improvements on NLG metrics. Secondly, these systems that achieve high performance on these metrics are not always factually complete or consistent due to both inadequate training and evaluation. Recent studies have shown the systems can be substantially improved by using new methods encouraging 1) the generation of domain entities consistent with the reference and 2) describing these entities in inferentially consistent ways. So far, these methods rely on weakly-supervised approaches (rule-based) and named entity recognition systems that are not specific to the chest X-ray domain. To overcome this limitation, we propose a new method, the RadGraph reward, to further improve the factual completeness and correctness of generated radiology reports. More precisely, we leverage the RadGraph dataset containing annotated chest X-ray reports with entities and relations between entities. On two open radiology report datasets, our system substantially improves the scores up to 14.2% and 25.3% on metrics evaluating the factual correctness and completeness of reports.

2021

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QIAI at MEDIQA 2021: Multimodal Radiology Report Summarization
Jean-Benoit Delbrouck | Cassie Zhang | Daniel Rubin
Proceedings of the 20th Workshop on Biomedical Language Processing

This paper describes the solution of the QIAI lab sent to the Radiology Report Summarization (RRS) challenge at MEDIQA 2021. This paper aims to investigate whether using multimodality during training improves the summarizing performances of the model at test-time. Our preliminary results shows that taking advantage of the visual features from the x-rays associated to the radiology reports leads to higher evaluation metrics compared to a text-only baseline system. These improvements are reported according to the automatic evaluation metrics METEOR, BLEU and ROUGE scores. Our experiments can be fully replicated at the following address: https://github.com/jbdel/vilmedic.

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MiniVQA - A resource to build your tailored VQA competition
Jean-Benoit Delbrouck
Proceedings of the Fifth Workshop on Teaching NLP

MiniVQA is a Jupyter notebook to build a tailored VQA competition for your students. The resource creates all the needed resources to create a classroom competition that engages and inspires your students on the free, self-service Kaggle platform. “InClass competitions make machine learning fun¡‘.

2020

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A Transformer-based joint-encoding for Emotion Recognition and Sentiment Analysis
Jean-Benoit Delbrouck | Noé Tits | Mathilde Brousmiche | Stéphane Dupont
Second Grand-Challenge and Workshop on Multimodal Language (Challenge-HML)

Understanding expressed sentiment and emotions are two crucial factors in human multimodal language. This paper describes a Transformer-based joint-encoding (TBJE) for the task of Emotion Recognition and Sentiment Analysis. In addition to use the Transformer architecture, our approach relies on a modular co-attention and a glimpse layer to jointly encode one or more modalities. The proposed solution has also been submitted to the ACL20: Second Grand-Challenge on Multimodal Language to be evaluated on the CMU-MOSEI dataset. The code to replicate the presented experiments is open-source .

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Modulated Fusion using Transformer for Linguistic-Acoustic Emotion Recognition
Jean-Benoit Delbrouck | Noé Tits | Stéphane Dupont
Proceedings of the First International Workshop on Natural Language Processing Beyond Text

This paper aims to bring a new lightweight yet powerful solution for the task of Emotion Recognition and Sentiment Analysis. Our motivation is to propose two architectures based on Transformers and modulation that combine the linguistic and acoustic inputs from a wide range of datasets to challenge, and sometimes surpass, the state-of-the-art in the field. To demonstrate the efficiency of our models, we carefully evaluate their performances on the IEMOCAP, MOSI, MOSEI and MELD dataset. The experiments can be directly replicated and the code is fully open for future researches.

2017

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An empirical study on the effectiveness of images in Multimodal Neural Machine Translation
Jean-Benoit Delbrouck | Stéphane Dupont
Proceedings of the 2017 Conference on Empirical Methods in Natural Language Processing

In state-of-the-art Neural Machine Translation (NMT), an attention mechanism is used during decoding to enhance the translation. At every step, the decoder uses this mechanism to focus on different parts of the source sentence to gather the most useful information before outputting its target word. Recently, the effectiveness of the attention mechanism has also been explored for multi-modal tasks, where it becomes possible to focus both on sentence parts and image regions that they describe. In this paper, we compare several attention mechanism on the multi-modal translation task (English, image → German) and evaluate the ability of the model to make use of images to improve translation. We surpass state-of-the-art scores on the Multi30k data set, we nevertheless identify and report different misbehavior of the machine while translating.